Construction of Electrospray Ion Source for Magnetic Sector Mass Spectrometer.

Tuning of an electrospray ionization source for maximum peptide-ion transmission into a mass spectrometer.

We describe assembly and optimization of a continuous flow nanoelectrospray source for high-performance analysis on a routine basis. It is derived from an inJection adaptable Fine Ionization Source ("JaFIS"), previously shown to be durable and easy to use (Geromanos, S.; et al. Rapid Commun. Mass Spectrom. 1998, 12, 551-556) and now modified for maximum sensitivity. Proper design, manufacturing...

Design and performance of a high resolution electrospray ion source for a magnetic sector mass spectrometer with a heated capillary inlet.

The design and performance of an electrospray ion source for a high resolution magnetic sector mass spectrometer that utilizes a heated capillary has been presented. Low pressure, high sensitivity, stable electrospray, low flow rates, and low electronic noise were important factors in achieving high resolution electrospray mass spectrometry. A unit mass resolution has been achieved for biomolec...

Electrospray Ionization/ion Mobility Spectrometer/cylindrical Ion Trap Mass Spectrometer System for In-situ Detection of Organic Compounds

SPECTROMETER SYSTEM FOR IN-SITU DETECTION OF ORGANIC COMPOUNDS I. Kanik, P.V. Johnson, L. W. Beegle, R. G. Cooks, B. C. Laughlin and H. H. Hill, Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109, [email protected], [email protected], Department of Chemistry Purdue University West Lafayette IN, 47907-0393, [email protected] Depa...

An interface with a linear quadrupole ion guide for an electrospray-ion trap mass spectrometer system.

A new ion sampling interface for an electrospray ionization 3D ion trap mass spectrometer system is described. The interface uses linear rf quadrupoles as ion guides and ion traps to enhance the performance of the 3D trap. Trapping ions in the linear quadrupoles is demonstrated to improve the duty cycle of the system. Dipolar excitation of ions trapped in a linear quadrupole is used to eject un...

MEMS ion source for mass spectrometer integrated on a chip